Source:http://linkedlifedata.com/resource/pubmed/id/12682546
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-4-8
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pubmed:abstractText |
Glutathione S-transferase enzymes mediate exposure to cytotoxic and genotoxic agents and may be involved in cancer susceptibility. Both glutathione S-transferase mu 1 (GSTM1) and GST theta 1 (GSTT1) genes have a null variant allele in which the entire gene is absent. The association of glutathione S-transferase null genotype and risk of developing colorectal cancer is not yet fully clarified.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0012-3706
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
510-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12682546-Adenocarcinoma,
pubmed-meshheading:12682546-Age of Onset,
pubmed-meshheading:12682546-Brazil,
pubmed-meshheading:12682546-Colorectal Neoplasms,
pubmed-meshheading:12682546-Female,
pubmed-meshheading:12682546-Genotype,
pubmed-meshheading:12682546-Glutathione Transferase,
pubmed-meshheading:12682546-Humans,
pubmed-meshheading:12682546-Male,
pubmed-meshheading:12682546-Middle Aged,
pubmed-meshheading:12682546-Seroepidemiologic Studies
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pubmed:year |
2003
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pubmed:articleTitle |
Possible influence of glutathione S-transferase GSTT1 null genotype on age of onset of sporadic colorectal adenocarcinoma.
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pubmed:affiliation |
Department of Internal Medicine, State University of Campinas, Campinas, São Paulo, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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