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pubmed-article:12675197pubmed:abstractTextChungsim-Yeunja-Tang is a prescription for the Taeumin cerebral infarction (CI) patients according to Sasang constitutional philosophy. Taeumin patients with CI were treated with CY-Tang during the acute stage. Clinical signs of CI disappeared markedly in about 2 weeks after oral administration of CY-Tang in all patients. The mean interleukin (IL)-2 plasma levels were slightly lower in the patients with CI than in the normal groups, whereas the mean TNF-alpha, IL-4, IL-6, and IgE levels were significantly higher in the patients with CI. There were no significant differences in interferon-gamma (IFN-gamma) levels between the groups. Serum IFN-gamma and IL-2 levels derived from (Th) 1 cells were significantly elevated in the patients with CI by CY-Tang administration. Significant reduced plasma levels of IL-4 and IL-6 derived from Th2 cells and IgE were observed in the patients treated with CY-Tang. Plasma levels TNF-alpha derived from Th1 significantly increased in the patients treated with CY-Tang. During the period of CY-Tang administration, there were no other adverse effects. The data indicate that CY-Tang has a good CI treatment effect, and that its action may be due to the regulation of cytokine production.lld:pubmed
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pubmed-article:12675197pubmed:dateRevised2009-5-14lld:pubmed
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pubmed-article:12675197pubmed:articleTitleRegulation of TH1/TH2 cytokine production by Chungsim-Yeunja-Tang in patients with cerebral infarction.lld:pubmed
pubmed-article:12675197pubmed:affiliationDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan-city, Chonbuk, South Korea.lld:pubmed
pubmed-article:12675197pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12675197pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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