Source:http://linkedlifedata.com/resource/pubmed/id/12675197
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2003-4-4
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| pubmed:abstractText |
Chungsim-Yeunja-Tang is a prescription for the Taeumin cerebral infarction (CI) patients according to Sasang constitutional philosophy. Taeumin patients with CI were treated with CY-Tang during the acute stage. Clinical signs of CI disappeared markedly in about 2 weeks after oral administration of CY-Tang in all patients. The mean interleukin (IL)-2 plasma levels were slightly lower in the patients with CI than in the normal groups, whereas the mean TNF-alpha, IL-4, IL-6, and IgE levels were significantly higher in the patients with CI. There were no significant differences in interferon-gamma (IFN-gamma) levels between the groups. Serum IFN-gamma and IL-2 levels derived from (Th) 1 cells were significantly elevated in the patients with CI by CY-Tang administration. Significant reduced plasma levels of IL-4 and IL-6 derived from Th2 cells and IgE were observed in the patients treated with CY-Tang. Plasma levels TNF-alpha derived from Th1 significantly increased in the patients treated with CY-Tang. During the period of CY-Tang administration, there were no other adverse effects. The data indicate that CY-Tang has a good CI treatment effect, and that its action may be due to the regulation of cytokine production.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Drugs, Chinese Herbal,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
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| pubmed:issn |
0892-3973
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
29-39
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| pubmed:dateRevised |
2009-5-14
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| pubmed:meshHeading |
pubmed-meshheading:12675197-Adult,
pubmed-meshheading:12675197-Aged,
pubmed-meshheading:12675197-Cerebral Infarction,
pubmed-meshheading:12675197-Cytokines,
pubmed-meshheading:12675197-Drugs, Chinese Herbal,
pubmed-meshheading:12675197-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12675197-Female,
pubmed-meshheading:12675197-Humans,
pubmed-meshheading:12675197-Immunoglobulin E,
pubmed-meshheading:12675197-Interferon-gamma,
pubmed-meshheading:12675197-Interleukin-2,
pubmed-meshheading:12675197-Interleukin-4,
pubmed-meshheading:12675197-Interleukin-6,
pubmed-meshheading:12675197-Male,
pubmed-meshheading:12675197-Middle Aged,
pubmed-meshheading:12675197-Phytotherapy,
pubmed-meshheading:12675197-Th1 Cells,
pubmed-meshheading:12675197-Th2 Cells,
pubmed-meshheading:12675197-Tumor Necrosis Factor-alpha
|
| pubmed:year |
2003
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| pubmed:articleTitle |
Regulation of TH1/TH2 cytokine production by Chungsim-Yeunja-Tang in patients with cerebral infarction.
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| pubmed:affiliation |
Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan-city, Chonbuk, South Korea.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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