Source:http://linkedlifedata.com/resource/pubmed/id/12674041
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2003-4-3
|
| pubmed:abstractText |
Cinoxacin is an oral synthetic antibacterial agent, of the second generation quinolones group, with excellent efficacy in respiratory, intra-abdominal, pelvic, and skin and soft tissue infections. Overall, quinolones are well tolerated drugs, although phototoxicity and photoallergenicity is well demonstrated experimentally. In this report we show you a case of a man who presented a anaphylactic reaction associated with myocardial infarction, after taking a capsule of cinoxacin. We suppose that there is a direct participation of the heart in anaphylactic reactions, because acttivated mast-cells mediators can determine cardiovascular effects. Then performed double-blind placebo controlled challenge test with an alternative drug. We did not observe any adverse immediate or late adverse reaction to this drug.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1764-1489
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
35
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
61-3
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| pubmed:dateRevised |
2008-2-26
|
| pubmed:meshHeading |
pubmed-meshheading:12674041-4-Quinolones,
pubmed-meshheading:12674041-Anaphylaxis,
pubmed-meshheading:12674041-Anti-Infective Agents,
pubmed-meshheading:12674041-Cinoxacin,
pubmed-meshheading:12674041-Double-Blind Method,
pubmed-meshheading:12674041-Humans,
pubmed-meshheading:12674041-Inflammation Mediators,
pubmed-meshheading:12674041-Male,
pubmed-meshheading:12674041-Mast Cells,
pubmed-meshheading:12674041-Middle Aged,
pubmed-meshheading:12674041-Myocardial Infarction,
pubmed-meshheading:12674041-Myocardium,
pubmed-meshheading:12674041-Paresthesia,
pubmed-meshheading:12674041-Postoperative Complications,
pubmed-meshheading:12674041-Pruritus,
pubmed-meshheading:12674041-Recurrence,
pubmed-meshheading:12674041-Tongue Diseases,
pubmed-meshheading:12674041-Urinary Bladder Neoplasms,
pubmed-meshheading:12674041-Urinary Diversion,
pubmed-meshheading:12674041-Urinary Tract Infections
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction.
|
| pubmed:affiliation |
Unità Operativa di Medicina Interna Ospedale di Faenza, Ravenna, Italy.
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| pubmed:publicationType |
Journal Article,
Case Reports
|