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rdf:type |
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lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0017262,
umls-concept:C0023689,
umls-concept:C0030705,
umls-concept:C0032854,
umls-concept:C0087111,
umls-concept:C0185117,
umls-concept:C0681842,
umls-concept:C1561558,
umls-concept:C1623145,
umls-concept:C2911684
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pubmed:issue |
1
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|
pubmed:dateCreated |
2003-4-3
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pubmed:abstractText |
The enzyme folylpolyglutamyl synthetase (FPGS) is involved in the resistance to methotrexate in tumor cell lines. The aim of the present study was to determine the impact of FPGS mRNA expression on resistance to methotrexate therapy in patients with rheumatoid arthritis (RA).
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12673886-Adult,
pubmed-meshheading:12673886-Aged,
pubmed-meshheading:12673886-Aged, 80 and over,
pubmed-meshheading:12673886-Antirheumatic Agents,
pubmed-meshheading:12673886-Arthritis, Rheumatoid,
pubmed-meshheading:12673886-Drug Resistance,
pubmed-meshheading:12673886-Female,
pubmed-meshheading:12673886-Humans,
pubmed-meshheading:12673886-Logistic Models,
pubmed-meshheading:12673886-Male,
pubmed-meshheading:12673886-Methotrexate,
pubmed-meshheading:12673886-Middle Aged,
pubmed-meshheading:12673886-Peptide Synthases,
pubmed-meshheading:12673886-RNA, Messenger,
pubmed-meshheading:12673886-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12673886-Severity of Illness Index
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pubmed:articleTitle |
Expression of folylpolyglutamyl synthetase predicts poor response to methotrexate therapy in patients with rheumatoid arthritis.
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pubmed:affiliation |
Division of Oncology, Department of Internal Medicine I, University of Vienna, Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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