rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2003-4-3
|
pubmed:abstractText |
Increased glucose consumption is a characteristic of malignant cells and in prostate carcinoma is associated with the proliferation of both androgen-dependent and independent cells. Transport of polar glucose across the nonpolar membrane relies on glucose transporter proteins, known as GLUTs. Increased expression of GLUT1 is a characteristic of many malignant cells. The authors characterized and cloned the cDNA for a novel glucose transporter, GLUT12, which was identified initially in malignant breast epithelial cells. To the authors' knowledge, there have been no reports on the expression of glucose transporters in the human prostate or human prostate carcinoma cells. The authors evaluated GLUT1 and GLUT12 expression in human prostate carcinoma cells.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0008-543X
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2003 American Cancer Society.
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pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
97
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2035-42
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12673735-Biopsy,
pubmed-meshheading:12673735-Blotting, Western,
pubmed-meshheading:12673735-DNA Primers,
pubmed-meshheading:12673735-Glucose Transporter Type 1,
pubmed-meshheading:12673735-Glucose Transporter Type 2,
pubmed-meshheading:12673735-Humans,
pubmed-meshheading:12673735-Immunoenzyme Techniques,
pubmed-meshheading:12673735-Male,
pubmed-meshheading:12673735-Microscopy, Confocal,
pubmed-meshheading:12673735-Monosaccharide Transport Proteins,
pubmed-meshheading:12673735-Prostatic Hyperplasia,
pubmed-meshheading:12673735-Prostatic Neoplasms,
pubmed-meshheading:12673735-RNA, Messenger,
pubmed-meshheading:12673735-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12673735-Tumor Cells, Cultured,
pubmed-meshheading:12673735-Tumor Markers, Biological
|
pubmed:year |
2003
|
pubmed:articleTitle |
Expression and localization of GLUT1 and GLUT12 in prostate carcinoma.
|
pubmed:affiliation |
Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Melbourne, Australia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|