| pubmed-article:12668465 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12668465 | lifeskim:mentions | umls-concept:C1518457 | lld:lifeskim |
| pubmed-article:12668465 | lifeskim:mentions | umls-concept:C0043301 | lld:lifeskim |
| pubmed-article:12668465 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:12668465 | lifeskim:mentions | umls-concept:C0205431 | lld:lifeskim |
| pubmed-article:12668465 | lifeskim:mentions | umls-concept:C0439794 | lld:lifeskim |
| pubmed-article:12668465 | lifeskim:mentions | umls-concept:C0585064 | lld:lifeskim |
| pubmed-article:12668465 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:12668465 | pubmed:dateCreated | 2003-4-1 | lld:pubmed |
| pubmed-article:12668465 | pubmed:abstractText | Multiple dense phases of nucleosome core particles (NCPs) were formed in controlled ionic conditions (15-160 mM monovalent salt, no divalent ions), under osmotic pressures ranging from 4.7 x 10(5) to 2.35 x 10(6) Pa. We present here the x-ray diffraction analysis of these phases. In the lamello-columnar phase obtained at low salt concentration (<25 mM), NCPs stack into columns that align to form bilayers, kept separated from one another by a layer of solvent. NCPs form a monoclinic lattice in the plane of the bilayer. For high salt concentration (>50 mM), NCPs order into either a two-dimensional columnar hexagonal phase or into three-dimensional orthorhombic (quasi-hexagonal) crystals. The lamellar and hexagonal (or quasi-hexagonal) organizations coexist in the intermediate salt range; their demixing requires a long time. For an applied pressure P = 4.7 10(5) Pa, the calculated NCPs concentration ranges from approximately 280 to 320 mg/ml in the lamello-columnar phase to 495 to 585 mg/ml in the three-dimensional orthorhombic phase. These concentrations cover the concentration of the living cell. | lld:pubmed |
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| pubmed-article:12668465 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12668465 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12668465 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12668465 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12668465 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12668465 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12668465 | pubmed:issn | 0006-3495 | lld:pubmed |
| pubmed-article:12668465 | pubmed:author | pubmed-author:MangenotStéph... | lld:pubmed |
| pubmed-article:12668465 | pubmed:author | pubmed-author:LeforestierAm... | lld:pubmed |
| pubmed-article:12668465 | pubmed:author | pubmed-author:DurandDominiq... | lld:pubmed |
| pubmed-article:12668465 | pubmed:author | pubmed-author:LivolantFranç... | lld:pubmed |
| pubmed-article:12668465 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12668465 | pubmed:volume | 84 | lld:pubmed |
| pubmed-article:12668465 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12668465 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12668465 | pubmed:pagination | 2570-84 | lld:pubmed |
| pubmed-article:12668465 | pubmed:dateRevised | 2010-9-14 | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:meshHeading | pubmed-meshheading:12668465... | lld:pubmed |
| pubmed-article:12668465 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12668465 | pubmed:articleTitle | X-ray diffraction characterization of the dense phases formed by nucleosome core particles. | lld:pubmed |
| pubmed-article:12668465 | pubmed:affiliation | Laboratoire de Physique des Solides, Université Paris-Sud, 91405 Orsay Cédex, France. | lld:pubmed |
| pubmed-article:12668465 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12668465 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12668465 | lld:pubmed |
