|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0030705,
umls-concept:C0036341,
umls-concept:C0037047,
umls-concept:C0162783,
umls-concept:C0205161,
umls-concept:C0205266,
umls-concept:C0376335,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2003-4-1
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|
pubmed:abstractText |
The identification of neurobiological intermediate phenotypes may hasten the search for susceptibility genes in complex psychiatric disorders such as schizophrenia. Earlier family studies have suggested that deficits in executive cognition and working memory may be related to genetic susceptibility for schizophrenia, but the biological basis for this behavioral phenotype has not been identified.
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|
pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0002-953X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
160
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
709-19
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:12668360-Adult,
pubmed-meshheading:12668360-Catechol O-Methyltransferase,
pubmed-meshheading:12668360-Cognition,
pubmed-meshheading:12668360-Cognition Disorders,
pubmed-meshheading:12668360-Cohort Studies,
pubmed-meshheading:12668360-Female,
pubmed-meshheading:12668360-Functional Laterality,
pubmed-meshheading:12668360-Genetic Predisposition to Disease,
pubmed-meshheading:12668360-Humans,
pubmed-meshheading:12668360-Magnetic Resonance Imaging,
pubmed-meshheading:12668360-Male,
pubmed-meshheading:12668360-Memory,
pubmed-meshheading:12668360-Neuropsychological Tests,
pubmed-meshheading:12668360-Phenotype,
pubmed-meshheading:12668360-Polymorphism, Genetic,
pubmed-meshheading:12668360-Prefrontal Cortex,
pubmed-meshheading:12668360-Risk Factors,
pubmed-meshheading:12668360-Schizophrenia,
pubmed-meshheading:12668360-Schizophrenic Psychology,
pubmed-meshheading:12668360-Siblings
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|
pubmed:year |
2003
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|
pubmed:articleTitle |
Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia.
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|
pubmed:affiliation |
Clinical Brain Disorders Branch, IRP, NIMH, NIH, Bethesda, MD 20982-1389, USA. callicoj@intra.nimh.nih.gov
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
