Linked Life Data

12666148

Source:http://linkedlifedata.com/resource/pubmed/id/12666148

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2003-3-31
pubmed:abstractText
In the last decade, the demand for high-throughput DNA analysis methods has dramatically increased, mainly due to the advent of the human genome sequencing project that is now nearing completion. Even though mass spectrometry did not contribute to that project, it is clear that it will have an important role in the post-genome sequencing era, in genomics and proteomics. In genomics, mainly matrix-assisted laser desorption/ionization (MALDI) mass spectrometry will contribute to large-scale single nucleotide polymorphism (SNP) genotyping projects. Here, the development and history of DNA analysis by mass spectrometry is reviewed and put into the context with the requirements of genomics. All major contributions to the field and their status and limitations are described in detail.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0277-7037
pubmed:author
pubmed:copyrightInfo
Copyright 2003 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
388-418
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Genotyping single nucleotide polymorphisms by mass spectrometry.
pubmed:affiliation
Centre National de Génotypage, Bâtiment G2, 2 Rue Gaston Crémieux, 91057 Evry Cedex, France.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't