Linked Life Data

12662098

Source:http://linkedlifedata.com/resource/pubmed/id/12662098

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-3-28
pubmed:abstractText
The incubation of the diterpene 18-dihydroxy-9,13-epi-ent-pimara-7,15-diene (3) with the fungus Gibberella fujikuroi gave 14 metabolites, 4 and 6-18. The carbons functionalized were the C-20 methyl and all the secondaries, except C-12. The main reaction observed was the epoxidation of the 7,8-double bond, which rearranged to form 7-keto derivatives, such as 10-17, or the allylic alcohol 18. Compound 9 was the only one obtained in which the 7,8-double bond of the substrate remained unaltered. This work confirms that, in the feeding of this type of diterpene with this fungus, the oxidation at C-19, typical of the biosynthesis of gibberellins from ent-kaur-16-ene, is inhibited.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0163-3864
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
392-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Microbial transformation of 18-hydroxy-9,13-epi-ent-pimara-7,15-diene by Gibberella fujikuroi.
pubmed:affiliation
Instituto de Productos Naturales y Agrobiología, CSIC, P.O. Box 195, 38206-La Laguna, Tenerife, Canary Islands, Spain. bmfraga@ipna.csic.es
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't