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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-3-28
pubmed:abstractText
A dynamic mechanistic model of homeorhetic and homeostatic controls of pig growth was developed. The homeorhetic principles were based on changes in time of fractional rates of anabolism and catabolism of tissues. A minimum number of homeostatic principles integrated current data on plasma kinetics and the partitioning of nutrients between anabolism and catabolism of body tissues, and endogenous losses with integument and into the gut. The major features of the model are two levels of organization (tissue and plasma) and three body tissues (carcass proteins, visceral proteins, and body lipids). The protein tissues and plasma amino acids were subdivided into lysine, methionine and cystine, threonine, tryptophan, other essential AA, and nonessential AA compartments. Plasma glucose and fatty acids were also considered. Adenosine triphosphate and adenosine diphosphate were used to represent energy transformations, although these energy transformations were not included in the homeostatic control of pig growth. The mass variations within each of the 23 basic compartments were described with a specific deterministic, dynamic differential equation. The simulated metabolic rates of the protein and lipid tissues were similar to published data. The principal outputs from the model (protein and lipid gain, body weight, chemical body constituents, plasma parameters) showed that the proposed homeorhetic and homeostatic controls provide a mechanistic approach to modeling growth.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-8812
pubmed:author
pubmed:issnType
Print
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
683-96
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Modeling homeorhetic and homeostatic controls of pig growth.
pubmed:affiliation
UMR INRA-INAPG Physiologie de la Nutrition et Alimentation 75231, Paris, France.
pubmed:publicationType
Journal Article