Linked Life Data

12657998

Source:http://linkedlifedata.com/resource/pubmed/id/12657998

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-3-26
pubmed:abstractText
During carotid endarterectomy, we routinely monitor internal carotid artery pressure (P(ICA)) and middle cerebral artery flow velocity (V(MCA)). P(ICA) has been previously shown to accurately reflect pressure at the origin of the middle cerebral artery, even during times of rapidly changing pressure such as occurs with sudden occlusion of the common carotid artery. We retrospectively analyzed pressure recordings around the time of carotid cross clamping in 29 consecutive carotid endarterectomy operations. Suitable transcranial Doppler recordings of V(MCA) were available from eight of the operations. Comparing the cardiac cycle prior to cross clamping with the first complete cardiac cycle after cross clamping, the mean P(ICA) fell from 93 mm Hg to 62 mm Hg and the mean V(MCA) fell from 41 cm x sec-1 to 25 cm x sec-1. Over the subsequent 10 seconds, there was a further decrease in P(ICA) to 51 mm Hg (P <.0001), while V(MCA) changed in the opposite direction, increasing to 32 cm x sec-1 (P <.01). The patients with the greatest decrease in P(ICA) immediately on cross clamping also had the greatest additional decrease over the following 10 seconds (r = 0.74). The increase in V(MCA) during the first 10 seconds after carotid occlusion is well recognized and is presumed to be due to autoregulatory vasodilatation. The simultaneous decrease that we observed in P(ICA) indicates an increase in the pressure gradient along the collateral vessels, which is to be expected during a period of increasing flow along those vessels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0898-4921
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
126-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Cerebral hemodynamics immediately following carotid occlusion.
pubmed:affiliation
Department of Anaesthetics, University of Sydney, Sydney, Australia. tmcull@mail.usyd.edu.au
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't