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pubmed-article:12657166pubmed:abstractTextAlteration of glutamate and gamma-aminobutyrate system have been reported to be associated with neurodegenerative disorders and have been postulated to be involved in aluminum-induced neurotoxicity as well. Aluminum, an well known and commonly exposed neurotoxin, was found to alter glutamate and gamma-aminobutyrate levels as well as activities of associated enzymes with regional specificity. Protein malnutrition also reported to alter glutamate level and some of its metabolic enzymes. Thus the region-wise study of levels of brain glutamate and gamma-aminobutyrate system in protein adequacy and inadequacy may be worthwhile to understand the mechanism of aluminum-induced neurotoxicity.lld:pubmed
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pubmed-article:12657166pubmed:articleTitleDietary protein restriction causes modification in aluminum-induced alteration in glutamate and GABA system of rat brain.lld:pubmed
pubmed-article:12657166pubmed:affiliationDepartment of Physiology, Sikkim Manipal Institute of Medical Sciences, 5th Mile, Tadong, Gangtok 737102, Sikkim, India. nprasunpriya@hotmail.comlld:pubmed
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