rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2003-3-25
|
pubmed:abstractText |
To improve the therapeutic efficacy and minimize the toxicity of 5-fluorouracil (5-FU), intermittent therapy consisting of alternate 24-h intravenous infusion and based on differences in generation time (T(G)) between normal cells and tumor cells was investigated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0344-5704
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
51
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
240-6
|
pubmed:dateRevised |
2006-4-24
|
pubmed:meshHeading |
pubmed-meshheading:12655443-Adult,
pubmed-meshheading:12655443-Aged,
pubmed-meshheading:12655443-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12655443-Cell Cycle,
pubmed-meshheading:12655443-Diarrhea,
pubmed-meshheading:12655443-Drug Administration Schedule,
pubmed-meshheading:12655443-Female,
pubmed-meshheading:12655443-Humans,
pubmed-meshheading:12655443-Infusions, Intravenous,
pubmed-meshheading:12655443-Male,
pubmed-meshheading:12655443-Middle Aged,
pubmed-meshheading:12655443-Stomach Neoplasms,
pubmed-meshheading:12655443-Stomatitis,
pubmed-meshheading:12655443-Tumor Cells, Cultured
|
pubmed:year |
2003
|
pubmed:articleTitle |
Intermittent FLDP: 24-h infusion of 5-FU on days 1, 3 and 5 combined with low-dose cisplatin on days 1-5 for gastric cancer, and its pharmacologic and kinetic rationale.
|
pubmed:affiliation |
Department of Surgery 1, Fukushima Medical University, 1 Hikarigaoka, 960-1295, Fukushima, Japan. mterashi@fmu.ac.jp
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase I
|