|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2-4
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pubmed:dateCreated |
1975-12-30
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|
pubmed:abstractText |
BCG cell walls contain approximately 30% free lipids like other mycobacterial cell walls. The insoluble skeleton of the cell wall is made up of two covalently linked polymers, a peptidoglycan and an arabinogalactan mycolate, with which are associated non peptidoglycan amino acids and a glucan. We present data on two structural features: 1. The "non peptidoglycan" amino acids; they form two kinds of compounds: peptide chains which can be solubilized by proteolytic enzymes and a trypsin-chymotrypsin insensitive poly-alpha-L-glutamic acid. 2. Presence of meso-DAP-meso-DAP1) interpeptide linkages in the peptidoglycan: this new type represents at least 50% of the interpeptide linkages of the cell wall of the BCG strain.
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pubmed:language |
eng
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|
pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jul
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|
pubmed:issn |
0300-872X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
149
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
118-25
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|
pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:126548-Amino Acids,
pubmed-meshheading:126548-BCG Vaccine,
pubmed-meshheading:126548-Cell Wall,
pubmed-meshheading:126548-Chymotrypsin,
pubmed-meshheading:126548-Glycogen,
pubmed-meshheading:126548-Mycobacterium bovis,
pubmed-meshheading:126548-Mycolic Acids,
pubmed-meshheading:126548-Peptidoglycan,
pubmed-meshheading:126548-Polysaccharides, Bacterial,
pubmed-meshheading:126548-Trypsin
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|
pubmed:year |
1975
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|
pubmed:articleTitle |
Chemical structure of the cell wall of Mycobacterium tuberculosis var. bovis, strain BCG.
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pubmed:publicationType |
Journal Article
|
