Source:http://linkedlifedata.com/resource/pubmed/id/12653946
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-3-25
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pubmed:abstractText |
Salivary duct carcinoma is a highly malignant salivary gland tumour with aggressive clinical behaviour, characterized by histological resemblance to invasive ductal carcinoma of the breast. Amplification of HER-2/neu oncogene and over-expression of its gene product have both prognostic and therapeutic implications in breast cancer. Recent report on salivary duct carcinomas for HER-2/neu using immunohistochemistry (IHC) has shown over-expression in most cases. However, correlation between IHC and molecular genetic analysis of HER-2/neu in salivary duct carcinoma has not yet been performed.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0309-0167
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
348-56
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12653946-Adult,
pubmed-meshheading:12653946-Aged,
pubmed-meshheading:12653946-Aged, 80 and over,
pubmed-meshheading:12653946-Carcinoma,
pubmed-meshheading:12653946-Female,
pubmed-meshheading:12653946-Gene Amplification,
pubmed-meshheading:12653946-Gene Expression,
pubmed-meshheading:12653946-Genes, erbB-2,
pubmed-meshheading:12653946-Humans,
pubmed-meshheading:12653946-Immunoenzyme Techniques,
pubmed-meshheading:12653946-In Situ Hybridization, Fluorescence,
pubmed-meshheading:12653946-Male,
pubmed-meshheading:12653946-Middle Aged,
pubmed-meshheading:12653946-Parotid Neoplasms,
pubmed-meshheading:12653946-Receptor, erbB-2,
pubmed-meshheading:12653946-Salivary Ducts
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pubmed:year |
2003
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pubmed:articleTitle |
Expression of HER-2/neu gene and protein in salivary duct carcinomas of parotid gland as revealed by fluorescence in-situ hybridization and immunohistochemistry.
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pubmed:affiliation |
Department of Pathology, Medical Faculty, Charles University, Plzen, Czech Republic. skalova@fnplzen.cz
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pubmed:publicationType |
Journal Article
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