Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-3-25
pubmed:abstractText
Sensitivity of V79 Chinese hamster cells and V79 cells transfected with human MRP1 gene to several agents inducing oxidative stress was compared. Cells overexpressing MRP1 did not show increased resistance to tert-butyl hydroperoxide, diamide, paraquat, menadione, dichromate and carmustine as estimated by cell survival and DNA damage assessed by comet assay. These findings suggest that overexpression of MRP1 does not confer increased resistance to oxidative stress.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1071-5762
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-95
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed-meshheading:12653207-Animals, pubmed-meshheading:12653207-Bicyclo Compounds, pubmed-meshheading:12653207-Biological Transport, pubmed-meshheading:12653207-Blotting, Western, pubmed-meshheading:12653207-CHO Cells, pubmed-meshheading:12653207-Carmustine, pubmed-meshheading:12653207-Cell Membrane, pubmed-meshheading:12653207-Cell Survival, pubmed-meshheading:12653207-Comet Assay, pubmed-meshheading:12653207-Cricetinae, pubmed-meshheading:12653207-DNA Damage, pubmed-meshheading:12653207-Diamide, pubmed-meshheading:12653207-Dose-Response Relationship, Drug, pubmed-meshheading:12653207-Electrophoresis, Polyacrylamide Gel, pubmed-meshheading:12653207-Glutathione, pubmed-meshheading:12653207-Humans, pubmed-meshheading:12653207-Multidrug Resistance-Associated Proteins, pubmed-meshheading:12653207-Oxidative Stress, pubmed-meshheading:12653207-Paraquat, pubmed-meshheading:12653207-Potassium Dichromate, pubmed-meshheading:12653207-Transfection, pubmed-meshheading:12653207-Vitamin K 3, pubmed-meshheading:12653207-tert-Butylhydroperoxide
pubmed:year
2003
pubmed:articleTitle
MRP1-transfected cells do not show increased resistance against oxidative stress.
pubmed:affiliation
Department of Molecular Biophysics, University of Lód?, 90-237 Lód?, Poland. kbm@biol.uni.lodz.pl
pubmed:publicationType
Journal Article