Linked Life Data

12652907

Source:http://linkedlifedata.com/resource/pubmed/id/12652907

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2003-3-25
pubmed:databankReference
pubmed:abstractText
Cloning report of complete coding region of HLA-DRB1*1405 has never appeared in the literature. We have isolated and sequenced it from a B cell line with a DRB1*1405/1502 genotype. The sequence information of this gene and previously published DRB1 genes for the other DR serotypes facilitated us to find that the cytoplasmic domain sequences of DRB1 genes fall into three groups. It is known that antigen presenting cells are differentially activated when products of different MHC class II genes are triggered. Functional analyses would discern if these allelic differences in the cytoplasmic domain are of functional significance.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1042-5179
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-61
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Complete cDNA coding sequence of the HLA-DRB1*1405 allele.
pubmed:affiliation
Department of Bioregulatory Medicine and Rheumatology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. kohsaka.rheu@tmd.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't