Linked Life Data

12650987

Source:http://linkedlifedata.com/resource/pubmed/id/12650987

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2003-3-24
pubmed:abstractText
The teleostean diencephalon contains a relatively large number of dopaminergic neurons compared to other vertebrates. In the zebrafish, 17 groups of such neurons have been distinguished. One of the most unusual among these is the group of paraventricular organ-accompanying cells, which are easily distinguished by their large somal size, high tyrosine hydroxylase content, and characteristic dendritic architecture. This cell group is also heterogeneous-subsets of neurons can be identified on the bases of dendritic orientation. In this study, the number of paraventricular organ-accompanying neurons is counted in adult brain sections stained with anti-tyrosine hydroxylase antibodies. There is an average of 7.2+/-1.0 neurons on each side of the brain, and an average sum of 14+/-1.1 neurons on both sides. The average difference between the left and the right sides is 0.8+/-0.5 neurons. Neuron numbers between the two sides of the same brain are highly correlated. These results suggest that there is a relatively stringent regulation of paraventricular organ-accompanying neuron number in the zebrafish brain. The correlated left-right numbers suggests that genetic factors may play a major role in this regulation. The consistent and low cell number should be helpful in elucidating the number of subsets of these neurons, the anatomical and functional organization of some of the dopaminergic neurons along the paraventricular organ, as well as factors that play a role in regulating neuron numbers.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
967
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-72
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Consistency in the number of dopaminergic paraventricular organ-accompanying neurons in the posterior tuberculum of the zebrafish brain.
pubmed:affiliation
Department of Biology, Queens College, The City University of New York, 65-30 Kissena Boulevard, Flushing 11367, USA. pokay@qc.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't