rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2003-3-21
|
pubmed:abstractText |
Although ovarian clear cell adenocarcinoma (OCCA) and ovarian endometrioid adenocarcinoma (EC) are considered to be closely related to endometriosis, the mechanisms of carcinogenesis of these two malignancies and malignant transformation of endometriosis are unclear. In this study, we examined the biology of OCCA and EC by performing large-scale analysis of K-ras activation and p53 mutation and overexpression in these malignancies. The results were subsequently analyzed for correlation with the clinicopathologic data.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0090-8258
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
88
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
318-25
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12648581-Adenocarcinoma, Clear Cell,
pubmed-meshheading:12648581-Adult,
pubmed-meshheading:12648581-Aged,
pubmed-meshheading:12648581-Carcinoma, Endometrioid,
pubmed-meshheading:12648581-Codon,
pubmed-meshheading:12648581-Female,
pubmed-meshheading:12648581-Genes, p53,
pubmed-meshheading:12648581-Genes, ras,
pubmed-meshheading:12648581-Humans,
pubmed-meshheading:12648581-Immunohistochemistry,
pubmed-meshheading:12648581-Middle Aged,
pubmed-meshheading:12648581-Mutation,
pubmed-meshheading:12648581-Ovarian Neoplasms,
pubmed-meshheading:12648581-Polymerase Chain Reaction,
pubmed-meshheading:12648581-Prognosis,
pubmed-meshheading:12648581-Tumor Suppressor Protein p53
|
pubmed:year |
2003
|
pubmed:articleTitle |
p53 mutations and overexpression affect prognosis of ovarian endometrioid cancer but not clear cell cancer.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|