Source:http://linkedlifedata.com/resource/pubmed/id/12648540
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
2003-3-21
|
pubmed:abstractText |
Two bromophenols, together with three known compounds, were isolated from the methanolic extract of the marine alga, Rhodomela confervoides. By means of MS and NMR spectroscopic analyses, they were identified as 3-bromo-4-[2,3-dibromo-4,5-dihydroxyphenyl] methyl-5-(hydroxymethyl) 1,2-benzenediol (1) and 3-bromo-4-[2,3-dibromo-4,5-dihydroxyphenyl] methyl-5- (ethoxymethyl) 1,2-benzenediol (2). Three known compounds were also isolated, namely 3-bromo-4-[2,3-dibromo-4,5-dihydroxyphenyl] methyl-5-(methoxymethyl) 1,2-benzenediol (3), 4,4'- methylenebis [5,6-dibromo-1,2-benzenediol] (4) and bis (2,3-dibromo-4,5-dihydroxybenzyl) ether (5). Compound 5 was the most active against five strains of bacteria with the MIC less than 70 microg/ml, while compounds 2, 3 and 4 exhibited moderate activity.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0031-9422
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1221-4
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:12648540-Anti-Bacterial Agents,
pubmed-meshheading:12648540-Escherichia coli,
pubmed-meshheading:12648540-Hydrocarbons, Brominated,
pubmed-meshheading:12648540-Microbial Sensitivity Tests,
pubmed-meshheading:12648540-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:12648540-Phenols,
pubmed-meshheading:12648540-Pseudomonas aeruginosa,
pubmed-meshheading:12648540-Rhodophyta,
pubmed-meshheading:12648540-Staphylococcus aureus,
pubmed-meshheading:12648540-Staphylococcus epidermidis
|
pubmed:year |
2003
|
pubmed:articleTitle |
Antibacterial bromophenols from the marine red alga Rhodomela confervoides.
|
pubmed:affiliation |
Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, PR China. njxu1973@hotmail.com
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|