rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2003-3-21
|
pubmed:abstractText |
The production of proinflammatory cytokines activates the systemic inflammatory response in sepsis. Patients also develop a compensatory anti-inflammatory reaction, which may have an important down-regulatory effect on the overactive inflammation. However, the role of this anti-inflammatory response in sepsis is not completely clarified. In this prospective study, we investigated the relationship between the pro- and anti-inflammatory cytokine profiles in severe sepsis and their role in the development of multiple organ failure (MOF).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0001-5172
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
319-25
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12648199-Adult,
pubmed-meshheading:12648199-Blood Pressure,
pubmed-meshheading:12648199-Cardiac Output,
pubmed-meshheading:12648199-Cytokines,
pubmed-meshheading:12648199-Female,
pubmed-meshheading:12648199-Humans,
pubmed-meshheading:12648199-Interleukin-1,
pubmed-meshheading:12648199-Interleukin-10,
pubmed-meshheading:12648199-Interleukin-6,
pubmed-meshheading:12648199-Male,
pubmed-meshheading:12648199-Middle Aged,
pubmed-meshheading:12648199-Multiple Organ Failure,
pubmed-meshheading:12648199-Oxygen,
pubmed-meshheading:12648199-Prospective Studies,
pubmed-meshheading:12648199-Sepsis,
pubmed-meshheading:12648199-Vascular Resistance
|
pubmed:year |
2003
|
pubmed:articleTitle |
Anti-inflammatory cytokine response and the development of multiple organ failure in severe sepsis.
|
pubmed:affiliation |
Departments of Anaesthesia and Intensive Care, Tampere University Hospital, Tampere, Finland. pekka.loisa@phks.fi
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|