Source:http://linkedlifedata.com/resource/pubmed/id/12646504
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rdf:type | |
lifeskim:mentions |
umls-concept:C0003069,
umls-concept:C0007595,
umls-concept:C0015127,
umls-concept:C0162741,
umls-concept:C0179586,
umls-concept:C0205216,
umls-concept:C0301630,
umls-concept:C0740009,
umls-concept:C1314792,
umls-concept:C1422073,
umls-concept:C1422760,
umls-concept:C1450569,
umls-concept:C1522538,
umls-concept:C1657858,
umls-concept:C1706092,
umls-concept:C1706433
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pubmed:issue |
5
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pubmed:dateCreated |
2003-3-20
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pubmed:abstractText |
Cyclase-associated proteins (CAP) are multifunctional proteins involved in Ras-cAMP signalling and regulation of the actin cytoskeleton. It has recently been demonstrated that over-expression of AtCAP1 in transgenic arabidopsis plants causes severe morphological defects owing to loss of actin filaments. To test the generality of the function of AtCAP1 in plants, transgenic tobacco plants over-expressing an arabidopsis CAP (AtCAP1) under the regulation of a glucocorticoid-inducible promoter were produced. Over-expression of AtCAP1 in transgenic tobacco plants led to growth abnormalities, in particular a reduction in the size of leaves. Morphological alterations in leaves were the result of reduced elongation of epidermal and mesophyll cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0305-7364
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
599-603
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pubmed:dateRevised |
2009-10-19
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pubmed:meshHeading |
pubmed-meshheading:12646504-Arabidopsis,
pubmed-meshheading:12646504-Arabidopsis Proteins,
pubmed-meshheading:12646504-Cell Cycle Proteins,
pubmed-meshheading:12646504-Cell Size,
pubmed-meshheading:12646504-Gene Expression,
pubmed-meshheading:12646504-Genes, Plant,
pubmed-meshheading:12646504-Plant Leaves,
pubmed-meshheading:12646504-Plants, Genetically Modified,
pubmed-meshheading:12646504-Promoter Regions, Genetic,
pubmed-meshheading:12646504-Tobacco
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pubmed:year |
2003
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pubmed:articleTitle |
Over-expression of Arabidopsis CAP causes decreased cell expansion leading to organ size reduction in transgenic tobacco plants.
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pubmed:affiliation |
Institute of Molecular and Cellular Biosciences, University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-0032, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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