|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001465,
umls-concept:C0031638,
umls-concept:C0031640,
umls-concept:C0037633,
umls-concept:C0150369,
umls-concept:C0234621,
umls-concept:C0441655,
umls-concept:C0599956,
umls-concept:C1149866,
umls-concept:C1382100,
umls-concept:C1412691,
umls-concept:C1413553,
umls-concept:C1510438,
umls-concept:C1511790,
umls-concept:C1706498,
umls-concept:C1849508,
umls-concept:C1882074,
umls-concept:C2825492
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2003-3-19
|
|
pubmed:abstractText |
A phosphate chemosensor ensemble, [Zn(H-bpmp)(pyrocatechol violet)](+) is useful for a real-time assay of phosphodiesterases (PDEs) in a neutral aqueous solution. In addition, a simple and convenient screen and assay procedures for inhibitors of PDEs have been demonstrated using IBMX, a nonselective PDE inhibitor as an example.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0960-894X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
24
|
|
pubmed:volume |
13
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1079-82
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12643916-1-Methyl-3-isobutylxanthine,
pubmed-meshheading:12643916-3',5'-Cyclic-AMP Phosphodiesterases,
pubmed-meshheading:12643916-Adenosine Monophosphate,
pubmed-meshheading:12643916-Calorimetry,
pubmed-meshheading:12643916-Indicators and Reagents,
pubmed-meshheading:12643916-Kinetics,
pubmed-meshheading:12643916-Phosphodiesterase Inhibitors,
pubmed-meshheading:12643916-Solutions,
pubmed-meshheading:12643916-Spectrophotometry, Ultraviolet,
pubmed-meshheading:12643916-Thermodynamics
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
Visual detection of AMP and real-time monitoring of cyclic nucleotide phosphodiesterase (PDE) activity in neutral aqueous solution. Chemosensor-coupled assay of PDE and PDE inhibitors.
|
|
pubmed:affiliation |
Center for Integrated Molecular Systems and Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, San 31 Hyojadong, Pohang 790-784, South Korea.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
