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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-3-18
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pubmed:abstractText |
Countries with a low risk of hepatitis B (HB) lack data on the effectiveness of universal HB vaccination programs for children. British Columbia began a program in 1992, offering HB vaccination to 11 year olds. We conducted an anonymous, unlinked serologic survey 7 years later, analyzing a random sample of specimens (n = 1215) from women aged 15-44 years who had undergone antenatal rubella testing. Among those aged 15-19 years inclusive there was no evidence of chronic HB (HB surface antigen), the proportion with evidence of acute HB (anti-HB core antibody) was only 0.6% (compared with 6.5% for the entire sample), and evidence of protective immunity was strong: the prevalence of anti-HB surface antibody (anti-HBs) was 79.1% (compared with 41.4% for the entire sample) and the geometric mean titre was 34.9 IU/mL (compared with 0.6-0.8 IU/mL for the older groups [p < 0.001]).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0820-3946
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
168
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
703-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12642425-Acute Disease,
pubmed-meshheading:12642425-Adolescent,
pubmed-meshheading:12642425-Adult,
pubmed-meshheading:12642425-Age Distribution,
pubmed-meshheading:12642425-Biological Markers,
pubmed-meshheading:12642425-British Columbia,
pubmed-meshheading:12642425-Child,
pubmed-meshheading:12642425-Child Welfare,
pubmed-meshheading:12642425-Chronic Disease,
pubmed-meshheading:12642425-Female,
pubmed-meshheading:12642425-Health Surveys,
pubmed-meshheading:12642425-Hepatitis B,
pubmed-meshheading:12642425-Hepatitis B Antibodies,
pubmed-meshheading:12642425-Hepatitis B Core Antigens,
pubmed-meshheading:12642425-Hepatitis B Surface Antigens,
pubmed-meshheading:12642425-Humans,
pubmed-meshheading:12642425-Immunization Programs,
pubmed-meshheading:12642425-Mass Screening,
pubmed-meshheading:12642425-Pregnancy,
pubmed-meshheading:12642425-Pregnancy Complications, Infectious,
pubmed-meshheading:12642425-Prenatal Diagnosis,
pubmed-meshheading:12642425-Program Evaluation,
pubmed-meshheading:12642425-Risk Factors,
pubmed-meshheading:12642425-Seroepidemiologic Studies,
pubmed-meshheading:12642425-Women's Health
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pubmed:year |
2003
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pubmed:articleTitle |
Impact of universal preadolescent vaccination against hepatitis B on antenatal seroprevalence of hepatitis B markers in British Columbia women.
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pubmed:affiliation |
First Nations and Inuit Health Branch, Medical Programs, Pacific Region, Health Canada, Vancouver, BC. meenakshi_dawar@hc-sc.gc.ca
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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