Source:http://linkedlifedata.com/resource/pubmed/id/12636158
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2003-3-14
|
| pubmed:abstractText |
The objective of this study was to synthesize anhydride prodrugs for prolong action to shield the carboxylic acid group from irritative effects and to temporary hydrophobize the drug so that it becomes accessible to aqueous media when the anhydride residue is hydrolyzed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0724-8741
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
205-11
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:12636158-Anhydrides,
pubmed-meshheading:12636158-Animals,
pubmed-meshheading:12636158-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:12636158-Edema,
pubmed-meshheading:12636158-Female,
pubmed-meshheading:12636158-Prodrugs,
pubmed-meshheading:12636158-Rats,
pubmed-meshheading:12636158-Rats, Sprague-Dawley
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Anhydride prodrugs for nonsteroidal anti-inflammatory drugs.
|
| pubmed:affiliation |
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel 91120.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|