Source:http://linkedlifedata.com/resource/pubmed/id/12634542
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-3-13
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pubmed:abstractText |
Systemic hypoxia following surgical injury modulates cytokine and catecholamine responses. Endotoxin tolerance develops after pretreatment of animals with sublethal endotoxin doses and is characterized by a reduced inflammatory cytokine response to subsequent endotoxin challenges. The administration of endotoxin also attenuates ischemic injury of rat myocardial tissue following hypoxia, a phenomenon described as cross-tolerance. The objectives of this study were: 1) to determine whether endotoxin evokes a cross-tolerance to systemic hypoxia in rats; and 2) to estimate circulatory and pulmonary performance in rats with systemic hypoxia after endotoxin pretreatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-5282
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
584-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12634542-Adaptation, Physiological,
pubmed-meshheading:12634542-Animals,
pubmed-meshheading:12634542-Anoxia,
pubmed-meshheading:12634542-Blood Pressure,
pubmed-meshheading:12634542-Dose-Response Relationship, Drug,
pubmed-meshheading:12634542-Endotoxins,
pubmed-meshheading:12634542-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12634542-Epinephrine,
pubmed-meshheading:12634542-Inflammation,
pubmed-meshheading:12634542-Interleukin-6,
pubmed-meshheading:12634542-Male,
pubmed-meshheading:12634542-Myocardial Ischemia,
pubmed-meshheading:12634542-Rats,
pubmed-meshheading:12634542-Rats, Wistar,
pubmed-meshheading:12634542-Tumor Necrosis Factor-alpha
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pubmed:year |
2003
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pubmed:articleTitle |
Sublethal endotoxin administration evokes super-resistance to systemic hypoxia in rats.
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pubmed:affiliation |
Department of Gastrointestinal Surgery, University of Tokyo, Japan. naki@bd.mbn.or.jp
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pubmed:publicationType |
Journal Article
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