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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-3-13
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pubmed:abstractText |
EM-652 is a pure antiestrogen in human breast and uterine cancer cells that also reduces bone loss and plasma lipid levels in the rat. This study aimed to assess the ability of EM-652, alone or with dehydroepiandrosterone (DHEA), to prevent obesity and related metabolic abnormalities induced by an obesity-promoting diet and ovariectomy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1071-7323
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
477-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12634448-Adipose Tissue,
pubmed-meshheading:12634448-Animals,
pubmed-meshheading:12634448-Body Composition,
pubmed-meshheading:12634448-Body Weight,
pubmed-meshheading:12634448-Cholesterol,
pubmed-meshheading:12634448-Dehydroepiandrosterone,
pubmed-meshheading:12634448-Diet,
pubmed-meshheading:12634448-Dietary Fats,
pubmed-meshheading:12634448-Dietary Sucrose,
pubmed-meshheading:12634448-Eating,
pubmed-meshheading:12634448-Energy Intake,
pubmed-meshheading:12634448-Energy Metabolism,
pubmed-meshheading:12634448-Estrogen Antagonists,
pubmed-meshheading:12634448-Female,
pubmed-meshheading:12634448-Insulin Resistance,
pubmed-meshheading:12634448-Lipoprotein Lipase,
pubmed-meshheading:12634448-Liver,
pubmed-meshheading:12634448-Obesity,
pubmed-meshheading:12634448-Ovariectomy,
pubmed-meshheading:12634448-Piperidines,
pubmed-meshheading:12634448-Rats,
pubmed-meshheading:12634448-Rats, Sprague-Dawley,
pubmed-meshheading:12634448-Triglycerides,
pubmed-meshheading:12634448-Weight Gain
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pubmed:year |
2003
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pubmed:articleTitle |
The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity.
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pubmed:affiliation |
Centre de Recherche de l'Hôpital Laval and Département d'Anatomie et Physiologie, Faculté de Médecine, Université Laval, Quebec, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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