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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1976-7-6
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pubmed:abstractText |
We treated 50 patients with stage D carcinoma of the prostate with 15 mg. per kg. per day oral estramustine phosphate for 3 to 24 months. We are able to evaluate 44 patients. Objective remissions were induced in 8 of the 44 patients (19 per cent) and subjective remission occurred in all objective responders and in 7 additional patients for a subjective response of 15 of 44 (36 per cent). No hematologic or renal toxicity was encountered. Transient nausea occurred early in half of the patients and was dose limiting in 3 patients. One case of hepatic toxicity was seen. Oral estramustine phosphate is well tolerated and long-term therapy is feasible.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
409-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1263317-Administration, Oral,
pubmed-meshheading:1263317-Aged,
pubmed-meshheading:1263317-Dose-Response Relationship, Drug,
pubmed-meshheading:1263317-Drug Administration Schedule,
pubmed-meshheading:1263317-Estramustine,
pubmed-meshheading:1263317-Estrogens,
pubmed-meshheading:1263317-Humans,
pubmed-meshheading:1263317-Male,
pubmed-meshheading:1263317-Middle Aged,
pubmed-meshheading:1263317-Nitrogen Mustard Compounds,
pubmed-meshheading:1263317-Prostatic Neoplasms
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pubmed:year |
1976
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pubmed:articleTitle |
Extended therapy of stage D carcinoma of the prostate with oral estramustine phosphate.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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