Source:http://linkedlifedata.com/resource/pubmed/id/12632359
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-3-12
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pubmed:abstractText |
The etiology of Hirschsprung's-associated enterocolitis (HAEC) is unknown. Previous investigations have suggested that abnormal production of mucins may have an etiologic role. Recently, a series of mucin genes have been identified. MUC-2 is the predominant mucin expressed in humans. The authors have shown previously in vitro that use of MUC-2 can prevent bacterial translocation. Based on this, it was hypothesized that those patients with Hirschsprung's disease (HD) would have an abnormal production of MUC-2 compared with normal patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1531-5037
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2003, Elsevier Science (USA). All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
417-21; discussion 417-21
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12632359-Bacterial Translocation,
pubmed-meshheading:12632359-Case-Control Studies,
pubmed-meshheading:12632359-Diarrhea,
pubmed-meshheading:12632359-Enterocolitis,
pubmed-meshheading:12632359-Feces,
pubmed-meshheading:12632359-Female,
pubmed-meshheading:12632359-Hirschsprung Disease,
pubmed-meshheading:12632359-Humans,
pubmed-meshheading:12632359-Infant,
pubmed-meshheading:12632359-Male,
pubmed-meshheading:12632359-Mucin-2,
pubmed-meshheading:12632359-Mucins
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pubmed:year |
2003
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pubmed:articleTitle |
MUC-2 mucin production in Hirschsprung's disease: possible association with enterocolitis development.
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pubmed:affiliation |
Section of Pediatric Surgery, Department of Surgery, The University of Michigan Medical School and C.S. Mott Children's Hospital, Ann Arbor, Michigan 48109, USA.
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pubmed:publicationType |
Journal Article
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