|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2003-3-12
|
|
pubmed:abstractText |
Rotator cuff tendon cells (RCC) derived from surgical samples showed fibroblast-like morphology. Histological staining demonstrated collagen secretion by RCC. Immunohistological findings revealed that RCC secreted type I and III collagen, but not type II collagen. In addition, the SDS-PAGE analysis suggested that RCC predominantly produced type I collagen. Basic fibroblast growth factor (bFGF) had a stimulatory effect on the proliferation of RCC dose-dependently up to 1 ng/ml. Administration of bFGF suppressed the secretion of collagens from RCC in a dose-dependent manner.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0040-8727
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
198
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
207-14
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12630552-Cell Count,
pubmed-meshheading:12630552-Cell Division,
pubmed-meshheading:12630552-Cells, Cultured,
pubmed-meshheading:12630552-Collagen Type I,
pubmed-meshheading:12630552-Collagen Type III,
pubmed-meshheading:12630552-Dose-Response Relationship, Drug,
pubmed-meshheading:12630552-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:12630552-Fibroblast Growth Factor 2,
pubmed-meshheading:12630552-Fibroblasts,
pubmed-meshheading:12630552-Humans,
pubmed-meshheading:12630552-Rotator Cuff,
pubmed-meshheading:12630552-Tendons,
pubmed-meshheading:12630552-Tetrazolium Salts,
pubmed-meshheading:12630552-Thiazoles,
pubmed-meshheading:12630552-Time Factors
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
Effect of recombinant basic fibroblast growth factor (bFGF) on fibroblast-like cells from human rotator cuff tendon.
|
|
pubmed:affiliation |
Department of Orthopedic Surgery, Akita University School of Medicine, Akita 010-8543, Japan. shu@med.akita-u.ac.jp
|
|
pubmed:publicationType |
Journal Article
|
