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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-3-11
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pubmed:abstractText |
Leigh syndrome (LS) is a heterogeneous disorder, usually due to a defect in oxidative metabolism. Typically, signs and symptoms commence in infancy or childhood, although rare cases of adult onset have been described. Progressive deterioration is the norm. The authors describe a 22-year-old woman with partial cytochrome c oxidase deficiency who developed fulminant LS following an acute febrile illness and who subsequently showed dramatic clinical and neuroradiologic improvement.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
|
pubmed:issn |
1526-632X
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
865-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12629249-Adult,
pubmed-meshheading:12629249-Ascorbic Acid,
pubmed-meshheading:12629249-Brain,
pubmed-meshheading:12629249-Cytochrome-c Oxidase Deficiency,
pubmed-meshheading:12629249-Drug Therapy, Combination,
pubmed-meshheading:12629249-Female,
pubmed-meshheading:12629249-Humans,
pubmed-meshheading:12629249-Leigh Disease,
pubmed-meshheading:12629249-Magnetic Resonance Imaging,
pubmed-meshheading:12629249-Remission Induction,
pubmed-meshheading:12629249-Riboflavin,
pubmed-meshheading:12629249-Thiamine,
pubmed-meshheading:12629249-Ubiquinone
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pubmed:year |
2003
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|
pubmed:articleTitle |
Remarkable improvement in adult Leigh syndrome with partial cytochrome c oxidase deficiency.
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pubmed:affiliation |
School of Medicine, Oregon Health & Science University, Portland 97201, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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