Linked Life Data

12628164

Source:http://linkedlifedata.com/resource/pubmed/id/12628164

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-3-11
pubmed:abstractText
Little is known of molecular mechanisms of human mechanosensation. Only now are candidate eukaryotic sensors being identified. In contrast, bacterial sensors, including mechanosensitive channels, have been cloned, sequenced, reconstituted, and functional mutants characterized. Moreover, crystal structures for bacterial mechanosensitive channels have been resolved and structural gating transitions predicted. These studies give clues to general principles underlying the ability of a membrane protein to sense and respond to perturbations of its lipid environment that may be conserved between bacteria and humans.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0896-6273
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
731-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Molecular mechanisms of mechanosensation: big lessons from small cells.
pubmed:affiliation
Department of Physiology, University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA. paul.blount@utsouthwestern.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Review, Research Support, Non-U.S. Gov't