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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-3-7
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pubmed:abstractText |
The level of alpha(V)beta(3) integrins on endothelial cells is elevated in angiogenesis. The high binding specificity to alpha(V)beta(3) integrins of peptides containing Arg-Gly-Asp (RGD) residues suggests that the radiolabeled RGD peptides may be useful as tumor specific imaging agents. In this research, cyclised peptides containing Arg-Gly-Asp (RGD) and Arg-Gly-Glu (RGE, as control) residues were conjugated with HYNIC and labeled with (99m)Tc.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/6-hydrazinopyridine-3-carboxylic...,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/EDDA,
http://linkedlifedata.com/resource/pubmed/chemical/Edetic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Glycine,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrazines,
http://linkedlifedata.com/resource/pubmed/chemical/Integrins,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Nicotinic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides,
http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium,
http://linkedlifedata.com/resource/pubmed/chemical/arginyl-glycyl-aspartic acid,
http://linkedlifedata.com/resource/pubmed/chemical/tricine
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0969-8051
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12623113-Blood Proteins,
pubmed-meshheading:12623113-Cells, Cultured,
pubmed-meshheading:12623113-Edetic Acid,
pubmed-meshheading:12623113-Endothelium, Vascular,
pubmed-meshheading:12623113-Glycine,
pubmed-meshheading:12623113-Humans,
pubmed-meshheading:12623113-Hydrazines,
pubmed-meshheading:12623113-Integrins,
pubmed-meshheading:12623113-Ligands,
pubmed-meshheading:12623113-Metabolic Clearance Rate,
pubmed-meshheading:12623113-Nicotinic Acids,
pubmed-meshheading:12623113-Oligopeptides,
pubmed-meshheading:12623113-Protein Binding,
pubmed-meshheading:12623113-Radiopharmaceuticals,
pubmed-meshheading:12623113-Technetium,
pubmed-meshheading:12623113-Umbilical Veins
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pubmed:year |
2003
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pubmed:articleTitle |
In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands.
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pubmed:affiliation |
Division of Nuclear Medicine, Department of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Evaluation Studies
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