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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-3-6
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pubmed:abstractText |
The present study was designed to investigate whether the effects of dietary supplementation with alpha-lipoic acid could prevent the increase in mitochondrial superoxide production in the heart as well as the enhanced formation of advanced glycation end-products (AGE) that are associated with the development of hypertension and insulin resistance in chronically glucose-fed rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0895-7061
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-9
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pubmed:dateRevised |
2009-2-24
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pubmed:meshHeading |
pubmed-meshheading:12620694-Animals,
pubmed-meshheading:12620694-Antioxidants,
pubmed-meshheading:12620694-Blood Pressure,
pubmed-meshheading:12620694-Body Weight,
pubmed-meshheading:12620694-Diabetes Mellitus, Experimental,
pubmed-meshheading:12620694-Glucose,
pubmed-meshheading:12620694-Glycosylation End Products, Advanced,
pubmed-meshheading:12620694-Hyperglycemia,
pubmed-meshheading:12620694-Hypertension,
pubmed-meshheading:12620694-Insulin Resistance,
pubmed-meshheading:12620694-Male,
pubmed-meshheading:12620694-Myocardium,
pubmed-meshheading:12620694-Oxidative Stress,
pubmed-meshheading:12620694-Rats,
pubmed-meshheading:12620694-Rats, Sprague-Dawley,
pubmed-meshheading:12620694-Superoxides,
pubmed-meshheading:12620694-Thioctic Acid
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pubmed:year |
2003
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pubmed:articleTitle |
Lipoic acid prevents hypertension, hyperglycemia, and the increase in heart mitochondrial superoxide production.
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pubmed:affiliation |
Department of Physiology, Faculty of Medicine, University of Montreal, Montreal, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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