rdf:type |
|
lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0019704,
umls-concept:C0021201,
umls-concept:C0031437,
umls-concept:C0039194,
umls-concept:C0205217,
umls-concept:C0205251,
umls-concept:C0237753,
umls-concept:C0332281,
umls-concept:C0376249,
umls-concept:C0422792,
umls-concept:C1332700,
umls-concept:C1332714,
umls-concept:C1710133
|
pubmed:dateCreated |
2003-3-6
|
pubmed:abstractText |
The shift of the human immunodeficiency virus (HIV) from nonsyncytium inducing strains (NSI/R5) to syncytium inducing strains (SI/X4) seen in subtype B infections during progression to acquired immunodeficiency syndrome (AIDS) is less frequently reported in subtype C. NSI and SI strains differ in the co-receptor they utilize to infect a T-cell. We postulated that a larger pool of CD4 T cells expressing CCR5 would be present among individuals in the Indian population. To validate this hypothesis, we estimated the percentage of CD4 cells expressing CCR5 or CXCR4 molecules among healthy south Indian adults and HIV infected individuals.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0971-5916
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
116
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
90-5
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:12619446-Adult,
pubmed-meshheading:12619446-CD4 Lymphocyte Count,
pubmed-meshheading:12619446-CD4-Positive T-Lymphocytes,
pubmed-meshheading:12619446-Female,
pubmed-meshheading:12619446-Gene Frequency,
pubmed-meshheading:12619446-HIV Infections,
pubmed-meshheading:12619446-HIV-1,
pubmed-meshheading:12619446-Humans,
pubmed-meshheading:12619446-India,
pubmed-meshheading:12619446-Male,
pubmed-meshheading:12619446-Phenotype,
pubmed-meshheading:12619446-Receptors, CCR5,
pubmed-meshheading:12619446-Receptors, CXCR4,
pubmed-meshheading:12619446-Reference Values
|
pubmed:year |
2002
|
pubmed:articleTitle |
Increased number of CCR5+ CD4 T cells among south Indian adults probably associated with the low frequency of X4 phenotype of HIV-1 in India.
|
pubmed:affiliation |
Department of Clinical Virology, Christian Medical College, Vellore, India.
|
pubmed:publicationType |
Journal Article
|