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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1976-7-6
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pubmed:abstractText |
Four consecutive patients with systemic mastocytosis were studied. One patient had a malabsorption syndrome with only minor histological changes of the intestinal mucosa. Another patient with ulcer diathesis had a gastric secretory pattern resembling Zollinger-Ellison syndrome. Serum gastrin and histamine levels were consistently normal in all patients. Endoscopy of stomach and colon disclosed urticaria-like papulae either spontaneously or after topical provocation in all patients. No increase of mast cells was found in multiple mucosal biopsies. A markedly increased gastric tissue content of histamine was found, however, in the three patients studied. The findings suggest that urticaria-like lesions associated with a high tissue content of histamine may be more important that hyperhistaminaemia in causing the various gastrointestinal symptoms.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13070225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13381405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13388029,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13432786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13441357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13441358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13471655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13499582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13636820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13794076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13852143,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13869454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-13938969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14028718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14049348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14070428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14082741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14172469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14208164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14375386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-14773564,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4121709,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4176780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4464436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4805687,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4811016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4811022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4917502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-4967678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5010803,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5435650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5481779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5656235,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5678102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5728713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5764594,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-5900279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1261881-6034728
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0017-5749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-12
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pubmed:dateRevised |
2010-9-7
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pubmed:meshHeading |
pubmed-meshheading:1261881-Adult,
pubmed-meshheading:1261881-Cell Count,
pubmed-meshheading:1261881-Colon,
pubmed-meshheading:1261881-Gastric Juice,
pubmed-meshheading:1261881-Gastric Mucosa,
pubmed-meshheading:1261881-Gastrins,
pubmed-meshheading:1261881-Gastrointestinal Diseases,
pubmed-meshheading:1261881-Histamine,
pubmed-meshheading:1261881-Humans,
pubmed-meshheading:1261881-Malabsorption Syndromes,
pubmed-meshheading:1261881-Male,
pubmed-meshheading:1261881-Mast Cells,
pubmed-meshheading:1261881-Middle Aged,
pubmed-meshheading:1261881-Stomach Ulcer,
pubmed-meshheading:1261881-Urticaria,
pubmed-meshheading:1261881-Urticaria Pigmentosa
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pubmed:year |
1976
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pubmed:articleTitle |
Gastrointestinal involvement in systemic mastocytosis.
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pubmed:publicationType |
Journal Article,
Comparative Study
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