Source:http://linkedlifedata.com/resource/pubmed/id/12614488
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2003-4-10
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pubmed:abstractText |
The diagnosis of type 1 diabetes versus other forms of diabetes such as type 2 diabetes is paramount to guiding proper therapy. Several islet autoantibodies have been identified that serve to diagnose immune-mediated, type 1a diabetes in clinically ambiguous cases. These autoantibodies also serve to predict type 1 diabetes in nondiabetic individuals. The most useful islet autoantibodies include islet cell cytoplasmic autoantibodies, insulin autoantibodies, glutamic acid decarboxylase autoantibodies, and insulinoma-associated-2 autoantibodies. Once type 1 diabetes can be safely and reliably prevented, large-scale islet autoantibody screening programs of the general pediatric population may be warranted. It is controversial whether islet autoantibodies influence the course of type 1 diabetes following diagnosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamate Decarboxylase,
http://linkedlifedata.com/resource/pubmed/chemical/ICA512 autoantibody,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/islet cell antibody
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pubmed:status |
MEDLINE
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pubmed:issn |
1520-9156
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
817-39
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12614488-Animals,
pubmed-meshheading:12614488-Autoantibodies,
pubmed-meshheading:12614488-Biological Markers,
pubmed-meshheading:12614488-Diabetes Mellitus, Type 1,
pubmed-meshheading:12614488-Glutamate Decarboxylase,
pubmed-meshheading:12614488-Humans,
pubmed-meshheading:12614488-Insulin,
pubmed-meshheading:12614488-Islets of Langerhans
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pubmed:year |
2002
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pubmed:articleTitle |
Type 1 diabetes islet autoantibody markers.
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pubmed:affiliation |
Department of Pathology, Laboratory Medicine & Immunology, University of Florida, Gainesville, Florida 32610-0275, USA. winter@pathology.ufl.edu
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pubmed:publicationType |
Journal Article,
Review
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