Linked Life Data

12612035

Source:http://linkedlifedata.com/resource/pubmed/id/12612035

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-3-10
pubmed:abstractText
Rapidly adapting (RA), stretch-sensitive neurons were recorded in vitro, using an isolated preparation of skin and nerve from mouse hindlimb. The skin was stretched uniaxially using a pseudo-Gaussian noise stimulus. Loads and displacements were recorded as were spike responses of single RA afferent neurons. The goal was to determine what components of the mechanical stimulus were associated with spike responses. The association between stimuli and spike responses was measured using multiple logistic regression. Spike responses were strongly associated with the rate of change of stress and weakly associated with the rate of change of strain and with stress. There was no association between spike responses and strain. There were significant memory effects associated with each variable, and memory effects differed for each variable. The maximal effect of the rate of change of stress was observed 8-12 ms prior to a spike.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-3077
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1649-59
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Stretch responses of cutaneous RA afferent neurons in mouse hairy skin.
pubmed:affiliation
Department of Mechanical Engineering, University of Rome La Sapienza, 00184 Rome, Italy.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.