12608535

Source:http://linkedlifedata.com/resource/pubmed/id/12608535

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0162638, umls-concept:C0205369, umls-concept:C0242643, umls-concept:C0332281, umls-concept:C0450442, umls-concept:C1514559, umls-concept:C2349975
pubmed:issue	1
pubmed:dateCreated	2003-2-28
pubmed:abstractText	We have reported that overexpression of mdr1 P-glycoprotein (Pgp) is associated with a higher sensitivity to paclitaxel-induced apoptosis (1,2). The present study examined the substrate specificity of this phenomenon.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P30CA16058, http://linkedlifedata.com/resource/pubmed/grant/R37CA49816
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8406521
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0724-8741
pubmed:author	pubmed-author:AuJessie L SJL, pubmed-author:DongLiL, pubmed-author:JangSeong HSH, pubmed-author:KimJonghanJ, pubmed-author:WientjesM GuillaumeMG
pubmed:issnType	Print
pubmed:volume	20
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	45-50
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:12608535-Apoptosis, pubmed-meshheading:12608535-Dose-Response Relationship, Drug, pubmed-meshheading:12608535-Gene Expression Regulation, pubmed-meshheading:12608535-Humans, pubmed-meshheading:12608535-Microtubules, pubmed-meshheading:12608535-P-Glycoprotein, pubmed-meshheading:12608535-Tumor Cells, Cultured
pubmed:year	2003
pubmed:articleTitle	Enhanced drug-induced apoptosis associated with P-glycoprotein overexpression is specific to antimicrotubule agents.
pubmed:affiliation	College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't