Source:http://linkedlifedata.com/resource/pubmed/id/12607179
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-2-27
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pubmed:abstractText |
We present a cross-sectional, population-based neuropsychological study of systemic lupus erythematosus (SLE) patients identified within Tampere University Hospital district, Finland with 440,000 inhabitants. Patients with definite SLE in the age range of 16-65 years (n = 46) and matched controls (n = 46) underwent neurological examination and comprehensive neuropsychological testing. On the basis of medical examination, the SLE patients were divided into neuropsychiatric (NP+; n = 15) and nonneuropsychiatric (NP-; n = 31) cases. The neuropsychological test results revealed more prevalent cognitive impairment in the NP+ patients, indicating that this subgroup mostly accounts for neuropsychological changes in SLE. Most characteristic changes in NP+ were observed in domains of memory, psychomotor speed, and complex attention. This suggests nonspecific CNS involvement, which is in line with neurological manifestations of the disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1380-3395
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-51
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pubmed:dateRevised |
2008-4-14
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pubmed:meshHeading |
pubmed-meshheading:12607179-Adolescent,
pubmed-meshheading:12607179-Adult,
pubmed-meshheading:12607179-Aged,
pubmed-meshheading:12607179-Cognition Disorders,
pubmed-meshheading:12607179-Community Health Planning,
pubmed-meshheading:12607179-Cross-Sectional Studies,
pubmed-meshheading:12607179-Female,
pubmed-meshheading:12607179-Humans,
pubmed-meshheading:12607179-Lupus Erythematosus, Systemic,
pubmed-meshheading:12607179-Lupus Vasculitis, Central Nervous System,
pubmed-meshheading:12607179-Male,
pubmed-meshheading:12607179-Middle Aged,
pubmed-meshheading:12607179-Neurologic Examination,
pubmed-meshheading:12607179-Neuropsychological Tests
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pubmed:year |
2003
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pubmed:articleTitle |
Cognitive impairment in systemic lupus erythematosus and neuropsychiatric systemic lupus erythematosus: a population-based neuropsychological study.
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pubmed:affiliation |
Department of Psychiatry, Mental Health Center of Pori, Pori, Finland. jukka.loukkola@ppshp.fi
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pubmed:publicationType |
Journal Article,
Comparative Study
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