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pubmed:abstractText |
A recent study demonstrated the presence of protein-protein interactions among lens crystallins in a mammalian cell two-hybrid system assay and speculated about the significance of these interactions for protein solubility and lens transparency. The current study extends those findings to the following crystallin genes involved in some congenital cataracts: CRYAA (R116C), CRYAB (R120G), and CRYGC (T5P).
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pubmed:affiliation |
Center for Ophthalmic Research, Brigham and Women's Hospital, and the Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02115, USA.
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