Source:http://linkedlifedata.com/resource/pubmed/id/12598985
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2003-2-24
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pubmed:abstractText |
Laser- and sensitive charge-coupled device technology together with advanced mathematical modelling of photon propagation in tissue has prompted the development of novel optical imaging technologies. Fast surface-weighted imaging modalities, such as fluorescence reflectance imaging (FRI) and 3D quantitative fluorescence-mediated tomography have now become available [1, 2]. These technical advances are paralleled by a rapid development of a whole range of new optical contrasting strategies, which are designed to generate molecular contrast within a living organism. The combination of both, technical advances of light detection and the refinement of optical contrast media, finally yields a new spectrum of tools for in vivo molecular diagnostics. Whereas the technical aspects of optical imaging are covered in more detail in a previous review article in "European Radiology" [3], this article focuses on new developments in optical contrasting strategies and design of optical contrast agents for in vivo diagnostics.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0938-7994
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-43
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:12598985-Animals,
pubmed-meshheading:12598985-Contrast Media,
pubmed-meshheading:12598985-Diagnostic Imaging,
pubmed-meshheading:12598985-Fluorescence,
pubmed-meshheading:12598985-Fluorescent Dyes,
pubmed-meshheading:12598985-Humans,
pubmed-meshheading:12598985-Image Processing, Computer-Assisted,
pubmed-meshheading:12598985-Imaging, Three-Dimensional,
pubmed-meshheading:12598985-Mice,
pubmed-meshheading:12598985-Models, Theoretical,
pubmed-meshheading:12598985-Molecular Diagnostic Techniques,
pubmed-meshheading:12598985-Molecular Probes,
pubmed-meshheading:12598985-Neoplasms, Experimental,
pubmed-meshheading:12598985-Photons,
pubmed-meshheading:12598985-Rats,
pubmed-meshheading:12598985-Scattering, Radiation
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pubmed:year |
2003
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pubmed:articleTitle |
Optical-based molecular imaging: contrast agents and potential medical applications.
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pubmed:affiliation |
Department of Clinical Radiology, University of Münster, Albert-Schweitzer-Strasse 33, 48129 Münster, Germany. bremerc@uni-muenster.de
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pubmed:publicationType |
Journal Article,
Review
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