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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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pubmed:dateCreated |
2003-2-24
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|
pubmed:abstractText |
The role that growth factors and their receptors play in human cancer growth and progression makes them interesting targets for novel treatment modalities. Our approach consisted of active immunotherapy with the epidermal growth factor (EGF). Two pilot clinical trials were conducted to examine the safety and immunogenicity of a five-dose immunization protocol and to compare different adjuvants and treatment designs.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0923-7534
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pubmed:author |
pubmed-author:AlfonsoLL,
pubmed-author:CatalaMM,
pubmed-author:CrombetTT,
pubmed-author:GarciaBB,
pubmed-author:GonzalezGG,
pubmed-author:LabóGG,
pubmed-author:MuleaRR,
pubmed-author:NeningerEE,
pubmed-author:OsorioMM,
pubmed-author:PerezRR,
pubmed-author:TorresFF
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pubmed:issnType |
Print
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|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
461-6
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12598354-Adjuvants, Immunologic,
pubmed-meshheading:12598354-Adult,
pubmed-meshheading:12598354-Aged,
pubmed-meshheading:12598354-Aged, 80 and over,
pubmed-meshheading:12598354-Aluminum Hydroxide,
pubmed-meshheading:12598354-Antibody Formation,
pubmed-meshheading:12598354-Cancer Vaccines,
pubmed-meshheading:12598354-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:12598354-Epidermal Growth Factor,
pubmed-meshheading:12598354-Female,
pubmed-meshheading:12598354-Humans,
pubmed-meshheading:12598354-Lung Neoplasms,
pubmed-meshheading:12598354-Male,
pubmed-meshheading:12598354-Mannitol,
pubmed-meshheading:12598354-Middle Aged,
pubmed-meshheading:12598354-Oleic Acids,
pubmed-meshheading:12598354-Survival Analysis,
pubmed-meshheading:12598354-Vaccination
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pubmed:year |
2003
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|
pubmed:articleTitle |
Epidermal growth factor-based cancer vaccine for non-small-cell lung cancer therapy.
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pubmed:affiliation |
Center of Molecular Immunology, Hermanos Ameijeiras Hospital, Havana, Cuba. gisela@ict.cim.sld.cu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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