Source:http://linkedlifedata.com/resource/pubmed/id/12593713
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-2-20
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pubmed:abstractText |
Previously, we have documented that lung injury after trauma-hemorrhagic shock (T/HS) is related to gut injury and that females are more resistant to T/HS-induced lung injury than males. However, it is not known if the estrus cycle stage at the time of injury influences the female rat's resistance to T/HS-induced lung injury. Therefore, the goal of this study was to determine if the protective effect of the female gender on lung injury after T/HS is estrus cycle stage-specific. To test this hypothesis, female rats were subjected to trauma (laparotomy) and hemorrhagic shock (T/HS) during different stages of the estrus cycle. Female animals subjected to trauma with sham hemorrhagic shock served as the control.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1096-2964
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-40
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12593713-Animals,
pubmed-meshheading:12593713-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:12593713-Estrous Cycle,
pubmed-meshheading:12593713-Female,
pubmed-meshheading:12593713-Lung,
pubmed-meshheading:12593713-Lung Diseases,
pubmed-meshheading:12593713-Models, Animal,
pubmed-meshheading:12593713-Peroxidase,
pubmed-meshheading:12593713-Proteins,
pubmed-meshheading:12593713-Rats,
pubmed-meshheading:12593713-Rats, Sprague-Dawley,
pubmed-meshheading:12593713-Sex Factors,
pubmed-meshheading:12593713-Shock, Hemorrhagic,
pubmed-meshheading:12593713-Wounds and Injuries
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pubmed:year |
2001
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pubmed:articleTitle |
The female gender protects against pulmonary injury after trauma hemorrhagic shock.
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pubmed:affiliation |
Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Evaluation Studies
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