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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-2-19
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pubmed:abstractText |
Because lung cancer is the leading cause of cancer-related death, new approaches for preventing and controlling the disease are needed. Chemoprevention approaches are both feasible and effective. We evaluated the potential of deguelin, a natural plant product, as a lung cancer chemopreventive agent and investigated its mechanism of action.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0027-8874
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
291-302
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:12591985-Antineoplastic Agents,
pubmed-meshheading:12591985-Apoptosis,
pubmed-meshheading:12591985-Bronchial Neoplasms,
pubmed-meshheading:12591985-Cell Cycle,
pubmed-meshheading:12591985-Cells, Cultured,
pubmed-meshheading:12591985-Drug Screening Assays, Antitumor,
pubmed-meshheading:12591985-Genetic Vectors,
pubmed-meshheading:12591985-Humans,
pubmed-meshheading:12591985-Immunoblotting,
pubmed-meshheading:12591985-Lung Neoplasms,
pubmed-meshheading:12591985-Mitogen-Activated Protein Kinase Kinases,
pubmed-meshheading:12591985-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:12591985-Phosphorylation,
pubmed-meshheading:12591985-Protein-Serine-Threonine Kinases,
pubmed-meshheading:12591985-Proto-Oncogene Proteins,
pubmed-meshheading:12591985-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:12591985-Respiratory Mucosa,
pubmed-meshheading:12591985-Rotenone,
pubmed-meshheading:12591985-Signal Transduction,
pubmed-meshheading:12591985-Tumor Cells, Cultured
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pubmed:year |
2003
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pubmed:articleTitle |
Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells.
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pubmed:affiliation |
Box 432, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. hlee@mdanderson.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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