rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2003-2-19
|
pubmed:abstractText |
The antifungal activity of hevein-like proteins has been associated with their chitin-binding activities. Pn-AMP1 and Pn-AMP2, two hevein homologues from Pharbitis nil, show in vitro antifungal activities against both chitin and non-chitin containing fungi. Purified Pn-AMPs retained antifungal activities only under non-reducing conditions. When Pn-AMP2 cDNA was constitutively expressed in tomato (Lycopersicon esculentum) plants under the control of CaMV35S promoter, the transgenic plants showed enhanced resistance against both the non-chitinous fungus Phytophthora capsici, and the chitin-containing fungus Fusarium oxysporum. Thus, the chitin component in the fungal cell wall is not an absolute requirement for Pn-AMP's antifungal activities. These results when considered together suggest that Pn-AMPs have the potential for developing transgenic plants resistant to a wide range of phytopathogenic fungi.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0031-9422
|
pubmed:author |
pubmed-author:ChoMoo JeMJ,
pubmed-author:ChunHyun JinHJ,
pubmed-author:JeongByoung RyongBR,
pubmed-author:KarigarChandrakantC,
pubmed-author:KimDoh HoonDH,
pubmed-author:KimYoung HoeYH,
pubmed-author:KooJa ChoonJC,
pubmed-author:KwakSang-SooSS,
pubmed-author:LeeBoyoungB,
pubmed-author:LeeOk SunOS,
pubmed-author:NamJaesungJ,
pubmed-author:ParkNammiN,
pubmed-author:Prasad DTheerthaT,
pubmed-author:YunDae-JinDJ,
pubmed-author:YunJae-GilJG
|
pubmed:issnType |
Print
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1073-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12591259-Amino Acid Sequence,
pubmed-meshheading:12591259-Antifungal Agents,
pubmed-meshheading:12591259-Blotting, Northern,
pubmed-meshheading:12591259-Chitin,
pubmed-meshheading:12591259-Convolvulaceae,
pubmed-meshheading:12591259-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:12591259-Fusarium,
pubmed-meshheading:12591259-Lycopersicon esculentum,
pubmed-meshheading:12591259-Microbial Sensitivity Tests,
pubmed-meshheading:12591259-Molecular Weight,
pubmed-meshheading:12591259-Phytophthora,
pubmed-meshheading:12591259-Plant Diseases,
pubmed-meshheading:12591259-Plant Proteins,
pubmed-meshheading:12591259-Plants, Genetically Modified,
pubmed-meshheading:12591259-Sequence Homology, Amino Acid
|
pubmed:year |
2003
|
pubmed:articleTitle |
Pn-AMPs, the hevein-like proteins from Pharbitis nil confers disease resistance against phytopathogenic fungi in tomato, Lycopersicum esculentum.
|
pubmed:affiliation |
Division of Applied Life Science (BK21 program), Gyeongsang National University, Jinju 660-701, South Korea.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|