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rdf:type |
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lifeskim:mentions |
umls-concept:C0002085,
umls-concept:C0012854,
umls-concept:C0057223,
umls-concept:C0184661,
umls-concept:C0332597,
umls-concept:C0449416,
umls-concept:C1182707,
umls-concept:C1285573,
umls-concept:C1332830,
umls-concept:C1442989,
umls-concept:C1707227
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pubmed:issue |
1-2
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pubmed:dateCreated |
2003-2-18
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pubmed:abstractText |
Hair roots provide a useful alternative to blood as a source of DNA for genotyping. Besides simple and non-invasive collections, the DNA extraction step is also easy to perform and is fast. The aim of our study is to determine if hair roots can be used to genotype all of the common CYP2D6 alleles for routine screening purposes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
329
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
61-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12589966-Alleles,
pubmed-meshheading:12589966-Cytochrome P-450 CYP2D6,
pubmed-meshheading:12589966-DNA,
pubmed-meshheading:12589966-Electrophoresis, Agar Gel,
pubmed-meshheading:12589966-Gene Duplication,
pubmed-meshheading:12589966-Genotype,
pubmed-meshheading:12589966-Hair,
pubmed-meshheading:12589966-Humans,
pubmed-meshheading:12589966-Isoenzymes,
pubmed-meshheading:12589966-Leukocytes,
pubmed-meshheading:12589966-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2003
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pubmed:articleTitle |
Standard CYP2D6 genotyping procedures fail for the CYP2D6*5 and duplication alleles when hair roots are used as a source of DNA.
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pubmed:affiliation |
Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan. usmpcrprob@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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