12588771

Source:http://linkedlifedata.com/resource/pubmed/id/12588771

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0031676, umls-concept:C0205369, umls-concept:C0205460, umls-concept:C0221198, umls-concept:C0243178, umls-concept:C0597152
pubmed:issue	2
pubmed:dateCreated	2003-2-17
pubmed:abstractText	Phosphatidylcholine hydroxyalkenals (PC-HAs) are a class of oxidized PCs derived from lipid peroxidation of arachidonate or linoleate at the sn-2 position to form terminal gamma-hydroxy, alpha-, and beta-unsaturated aldehydes. The aim of this study was to characterize some of their biological properties, ascertain the mechanism of their action, and assess whether they have in vivo relevance.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/GM 21248, http://linkedlifedata.com/resource/pubmed/grant/HL 53315
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9505803
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/4-hydroxy-2-nonenal, http://linkedlifedata.com/resource/pubmed/chemical/Acetylcysteine, http://linkedlifedata.com/resource/pubmed/chemical/Aldehydes, http://linkedlifedata.com/resource/pubmed/chemical/Cathepsin B, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol Esters, http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL, http://linkedlifedata.com/resource/pubmed/chemical/Lysine, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylcholines, http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids, http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles, http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	1524-4636
pubmed:author	pubmed-author:HoffHenry FHF, pubmed-author:HoppeGeorgeG, pubmed-author:O'NeilJuneJ, pubmed-author:SalomonRobert LRL, pubmed-author:WuZhipingZ
pubmed:issnType	Electronic
pubmed:day	1
pubmed:volume	23
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	275-82
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:12588771-Acetylcysteine, pubmed-meshheading:12588771-Aldehydes, pubmed-meshheading:12588771-Animals, pubmed-meshheading:12588771-Arteriosclerosis, pubmed-meshheading:12588771-Biological Transport, pubmed-meshheading:12588771-Cathepsin B, pubmed-meshheading:12588771-Cholesterol Esters, pubmed-meshheading:12588771-Chromatography, Liquid, pubmed-meshheading:12588771-Humans, pubmed-meshheading:12588771-Intracellular Membranes, pubmed-meshheading:12588771-Lipoproteins, LDL, pubmed-meshheading:12588771-Lysine, pubmed-meshheading:12588771-Lysosomes, pubmed-meshheading:12588771-Macrophages, Peritoneal, pubmed-meshheading:12588771-Mice, pubmed-meshheading:12588771-Oxidation-Reduction, pubmed-meshheading:12588771-Phosphatidylcholines, pubmed-meshheading:12588771-Phospholipids, pubmed-meshheading:12588771-Pyrroles, pubmed-meshheading:12588771-Spectrometry, Mass, Electrospray Ionization
pubmed:year	2003
pubmed:articleTitle	Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions.
pubmed:affiliation	Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, OH 44195, USA. hoffh@ccf.org
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S.