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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-2-14
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pubmed:abstractText |
The classical genetic map of Arabidopsis contains 462 genes with mutant phenotypes. Chromosomal locations of these genes have been determined over the past 25 years based on recombination frequencies with visible and molecular markers. The most recent update of the classical map was published in a special genome issue of Science that dealt with Arabidopsis (D.W. Meinke, J.M. Cherry, C. Dean, S.D. Rounsley, M. Koornneef [1998] Science 282: 662-682). We present here a comprehensive list and sequence-based map of 620 cloned genes with mutant phenotypes. This map documents for the first time the exact locations of large numbers of Arabidopsis genes that give a phenotype when disrupted by mutation. Such a community-based physical map should have broad applications in Arabidopsis research and should serve as a replacement for the classical genetic map in the future. Assembling a comprehensive list of genes with a loss-of-function phenotype will also focus attention on essential genes that are not functionally redundant and ultimately contribute to the identification of the minimal gene set required to make a flowering plant.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-10590158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-10617454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-11099033,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-11125061,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-11130711,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-11483584,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-11779812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-12140549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-12143962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-12376646,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-1346933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-1678137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-2901107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-8106085,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-8188214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-8264525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-9254694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-9628021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12586866-9784120
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0032-0889
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
409-18
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pubmed:dateRevised |
2010-9-14
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pubmed:meshHeading |
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pubmed:year |
2003
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pubmed:articleTitle |
A sequence-based map of Arabidopsis genes with mutant phenotypes.
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pubmed:affiliation |
Department of Plant Biology, Carnegie Institution, 260 Panama Street, Stanford, California 94305, USA. Meinke@okstate.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
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